Description

2-Acetamido-4-Methyl-5-Bromopyridine is a high-purity brominated pyridine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile halogenated scaffold for constructing complex molecules, enabling efficient downstream functionalization. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Acetamido-4-Methyl-5-Bromopyridine
CAS No.	142404-82-8
Molecular Formula	C8H9BrN2O
Molecular Weight	229.08 g/mol
Synonyms	5-Bromo-4-methyl-2-pyridinylacetamide; N-(5-Bromo-4-methyl-2-pyridinyl)acetamide; 2-Acetylamino-4-methyl-5-bromopyridine; 5-Bromo-4-methyl-2-acetamidopyridine; 2-Acetamido-5-bromo-4-methylpyridine; 5-Bromo-4-methyl-pyridin-2-yl-acetamide; Acetamide, N-(5-bromo-4-methyl-2-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 2-Acetamido-4-Methyl-5-Bromopyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.