Description

2-Acetylamino-5-Bromo-3-Methylpyridine is a high-purity, multi-functional pyridine derivative with significant utility in advanced organic synthesis. This compound serves as a critical building block for the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific bromo and acetylamino functionalities into heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the pyridine core is a common bioactive motif.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and production of advanced organic electronic materials and photoactive compounds.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and inhibitors for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Acetylamino-5-Bromo-3-Methylpyridine
CAS No.	142404-81-7
Molecular Formula	C8H9BrN2O
Molecular Weight	229.08 g/mol
Synonyms	5-Bromo-3-methyl-2-acetamidopyridine; N-(5-Bromo-3-methylpyridin-2-yl)acetamide; 2-Acetamido-5-bromo-3-methylpyridine; 2-Acetylamino-5-bromo-3-picoline; Acetamide, N-(5-bromo-3-methyl-2-pyridinyl)-; 5-Bromo-3-methyl-2-pyridinylacetamide
EINECS	Contact for details

Quality Control

Our 2-Acetylamino-5-Bromo-3-Methylpyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.