Description

17-Ethynyl-4-Estrene-3,17-Diol-3-Acetate-17-(3'-Acetoxy-2'-Butenoate) CAS NO 142154-46-9 is a high-purity, multi-functional steroid derivative used as a critical advanced intermediate in pharmaceutical synthesis. Its complex molecular structure, featuring both ethynyl and ester functionalities, makes it a versatile building block for developing novel therapeutic agents. This compound is essential for research and development laboratories and production facilities focused on creating next-generation steroid-based pharmaceuticals, including potential hormone therapies and anti-inflammatory drugs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the production of novel steroid-based active pharmaceutical ingredients (APIs).
• Hormone Analog Research: Used in the research and development of new ethisterone and related hormone analogs with modified biological activity.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic and pharmacodynamic properties.
• Process Development: Employed in scaling up synthetic routes for complex steroid molecules under Good Manufacturing Practice (GMP) conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and steroid chemistry studies.

Basic Information

Product Name	17-Ethynyl-4-Estrene-3,17-Diol-3-Acetate-17-(3'-Acetoxy-2'-Butenoate)
CAS No.	142154-46-9
Molecular Formula	C28H34O7
Molecular Weight	482.57 g/mol
Synonyms	17α-Ethynyl-4-estrene-3β,17β-diol 3-acetate 17-(3'-acetoxy-2'-butenoate); 17α-Ethynyl-3β,17β-dihydroxy-4-estren-3-yl acetate 17-(3-acetoxy-2-butenoate); Ethisterone 17-(3-acetoxy-2-butenoate) derivative; 17-Ethynyl-3,17-dihydroxy-4-estren-3-yl acetate 17-(3'-acetoxy-2'-butenoate); Pregna-4-ene derivative, 17-ethynyl-3,17-diol-3-acetate-17-(3-acetoxy-2-butenoate); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 17-Ethynyl-4-Estrene-3,17-Diol-3-Acetate-17-(3'-Acetoxy-2'-Butenoate) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical R&D. We adhere to ICH guidelines for stability and impurity profiling. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and conformity to client specifications. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under moisture-controlled conditions when necessary. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.