Description

(1-Hydroxymethyl-Cyclopropyl)-Acetic Acid Methyl Ester is a versatile cyclopropane derivative and a valuable bifunctional building block in advanced organic synthesis. Its structure, featuring both a hydroxymethyl and an ester group on a strained cyclopropane ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially those containing cyclopropane motifs known for their metabolic stability and conformational rigidity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane ring can enhance biological activity.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Material Science Research: Employed in the development of novel polymers and functional materials with unique properties derived from the strained ring system.
• Cross-Coupling Reactions: The functional groups make it a suitable substrate for various metal-catalyzed coupling reactions to create complex carbon skeletons.
• Chiral Synthesis: Useful in asymmetric synthesis for producing enantiomerically pure compounds, important for drug development.

Basic Information

Product Name	(1-Hydroxymethyl-Cyclopropyl)-Acetic Acid Methyl Ester
CAS No.	142148-13-8
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	Methyl (1-Hydroxymethylcyclopropyl)acetate; (1-Hydroxymethylcyclopropyl)acetic Acid Methyl Ester; Methyl 2-(1-(Hydroxymethyl)cyclopropyl)acetate; Cyclopropaneacetic acid, 1-(hydroxymethyl)-, methyl ester; Methyl (1-(hydroxymethyl)cyclopropyl)acetate; 2-(1-(Hydroxymethyl)cyclopropyl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our (1-Hydroxymethyl-Cyclopropyl)-Acetic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment. We can supply material compliant with various pharmacopeial standards upon request, supporting your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.