Description

4-(3'-Di(2-Chloroethyl)Aminopropionyl)Biphenyl is a specialized organic compound featuring a biphenyl core functionalized with a nitrogen mustard-linked propionyl group. This molecular architecture makes it a valuable intermediate in advanced chemical synthesis, particularly for research and development in targeted therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel bioactive molecules and prodrug systems.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of potential alkylating agent-based chemotherapeutics and targeted drug conjugates.
• Bioconjugation Research: Used in the development of antibody-drug conjugates (ADCs) and other targeted delivery systems due to its reactive nitrogen mustard moiety.
• Medicinal Chemistry: Serves as a core scaffold or intermediate for structure-activity relationship (SAR) studies in oncology and other therapeutic areas.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value organic molecules for academic and industrial research.
• Biochemical Probe Development: Utilized to create molecular probes for studying DNA interaction mechanisms and cellular response pathways.

Basic Information

Product Name	4-(3'-Di(2-Chloroethyl)Aminopropionyl)Biphenyl
CAS No.	142058-12-6
Molecular Formula	C21H25Cl2NO
Molecular Weight	378.34 g/mol
Synonyms	4-[3-[Bis(2-chloroethyl)amino]propanoyl]biphenyl; 4'-(3-Bis(2-chloroethyl)aminopropionyl)biphenyl; Biphenyl, 4'-[3-[bis(2-chloroethyl)amino]-1-oxopropyl]-; 4'-(3-Di(2-chloroethyl)aminopropionyl)biphenyl; 142058-12-6; 4-(3-Di(2-chloroethyl)aminopropionyl)biphenyl; Nitrogen mustard biphenyl derivative
EINECS	Contact for details

Quality Control

Every batch of 4-(3'-Di(2-Chloroethyl)Aminopropionyl)Biphenyl is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports critical R&D and cGMP-grade manufacturing requirements for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.