Description

2-Cbz-Amino-4-Phenylbut-3-Enoic Acid Methyl Ester is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block and intermediate in the production of complex pharmaceutical molecules and bioactive peptides. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of protease inhibitors, peptidomimetics, and other active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis (SPPS).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of novel therapeutic candidates.
• Chemical Biology: Employed in the design and synthesis of enzyme substrates, inhibitors, and molecular probes.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals.

Basic Information

Product Name	2-Cbz-Amino-4-Phenylbut-3-Enoic Acid Methyl Ester
CAS No.	142054-92-0
Molecular Formula	C19H19NO4
Molecular Weight	325.36 g/mol
Synonyms	Methyl (2Z)-2-[[(benzyloxy)carbonyl]amino]-4-phenylbut-3-enoate; Methyl N-Cbz-2-amino-4-phenylbut-3-enoate; (Z)-Methyl 2-(((benzyloxy)carbonyl)amino)-4-phenylbut-3-enoate; N-Carbobenzoxy-2-amino-4-phenyl-3-butenoic acid methyl ester; Z-2-Amino-4-phenyl-3-butenoic acid methyl ester; Cbz-Phe(3,4-dehydro)-OMe; (Z)-Methyl 2-((((benzyloxy)carbonyl)amino)-4-phenylbut-3-enoate
EINECS	Contact for details

Quality Control

Our 2-Cbz-Amino-4-Phenylbut-3-Enoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.