Description

Eldacimibe is a high-purity, synthetic organic compound of significant interest in advanced pharmaceutical research and development. Its primary value lies in its role as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutic agents. This compound is essential for research organizations and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on metabolic and cardiovascular disease research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of proprietary drug candidates.
• Active Pharmaceutical Ingredient (API) Research: Used in preclinical and clinical research for developing new therapeutic entities.
• Biochemical Research: Employed as a reference standard or tool compound in metabolic pathway studies and target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional laboratories for pharmacological and medicinal chemistry investigations.

Basic Information

Product Name	Eldacimibe
CAS No.	141993-70-6
Molecular Formula	C29H21F3N2O4
Molecular Weight	518.48 g/mol
Synonyms	1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone; (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one; Ezetimibe Impurity; Ezetimibe Related Compound; SCH 58235; Zetia Impurity
EINECS	Contact for details

Quality Control

Our Eldacimibe is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product is suitable for research and development applications, with quality standards that can support pre-clinical studies. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by validated analytical methods (HPLC, GC, NMR) is provided with each batch to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.