Description

Miriplatin CAS NO 141977-79-9 is a platinum-based chemotherapeutic agent specifically designed for transarterial chemoembolization (TACE) in the treatment of hepatocellular carcinoma (HCC). This compound matters for its unique lipophilic properties, which enhance its retention within tumor tissues following intra-arterial administration, providing a targeted and sustained therapeutic effect. It is primarily needed by pharmaceutical manufacturers, oncology research institutions, and specialized compounding facilities developing or producing localized cancer therapies.

Application

• Primary Pharmaceutical Ingredient for the formulation of injectable suspensions used in transarterial chemoembolization (TACE).
• Active Pharmaceutical Ingredient (API) in the development of targeted liver cancer treatments.
• Research Chemical for preclinical and clinical studies investigating novel platinum-based chemotherapy mechanisms and delivery systems.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Key Intermediate in the synthesis of advanced, lipophilic platinum complexes for enhanced drug delivery.

Basic Information

Product Name	Miriplatin
CAS No.	141977-79-9
Molecular Formula	C₃₄H₆₀N₂O₈Pt
Molecular Weight	831.93 g/mol
Synonyms	Miriplatin Hydrate; SM-11355; (OC-6-43)-Diammine[cyclohexane-1,2-diamine-N,N']bis(tetradecanoato)platinum; (SP-4-2)-Diamminebis(tetradecanoato-κO)[(1R,2R)-1,2-cyclohexanediamine-κN,κN']platinum; cis-[(1R,2R)-1,2-Diaminocyclohexane]diamminebis(tetradecanoato)platinum(II); Liposomal Platinum Agent
EINECS	Contact for details

Quality Control

Our Miriplatin is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical active ingredients. Quality is assured through comprehensive analytical testing, including HPLC for purity and assay, determination of related substances and residual solvents, and confirmation of identity and crystalline form. A detailed Certificate of Analysis (COA) is provided with each batch, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, typically between 15°C and 25°C (59°F and 77°F), in a dry environment. The container should be kept securely sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.