Description

4-Bromomethyl-3-Nitrobenzoic Acid Succinimide Ester is a specialized bifunctional chemical building block that combines a reactive succinimide ester group with a bromomethyl aromatic moiety. This compound is critically important for its role in the synthesis of complex molecules, particularly as a versatile linker for bioconjugation and cross-linking applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing targeted drug delivery systems, diagnostic reagents, and novel polymers.

Application

• Bioconjugation Reagent: Used to covalently attach proteins, peptides, or antibodies to other molecules, surfaces, or nanoparticles via amine groups.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and antibody-drug conjugates (ADCs).
• Cross-linking Agent: Employed in polymer chemistry and materials science to create cross-linked networks for hydrogels or functionalized surfaces.
• Diagnostic Probe Synthesis: Facilitates the labeling of biomolecules with fluorescent dyes or other reporter groups for imaging and diagnostic assays.
• Solid-Phase Synthesis: Acts as a versatile linker for the immobilization of molecules on solid supports during combinatorial chemistry.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new chemical entities and biochemical pathways.

Basic Information

Product Name	4-Bromomethyl-3-Nitrobenzoic Acid Succinimide Ester
CAS No.	141884-92-6
Molecular Formula	C12H9BrN2O6
Molecular Weight	357.12 g/mol
Synonyms	3-Nitro-4-(bromomethyl)benzoic Acid N-Hydroxysuccinimide Ester; 4-(Bromomethyl)-3-nitrobenzoic Acid Succinimidyl Ester; 4-(Bromomethyl)-3-nitro-N-(2,5-dioxopyrrolidin-1-yl)benzamide; 3-Nitro-4-(bromomethyl)benzoyloxysuccinimide; BNPS; BNBS Ester; Succinimidyl 4-(Bromomethyl)-3-nitrobenzoate; Bromomethyl Nitrobenzoyl Succinimide Ester
EINECS	Contact for details

Quality Control

Our 4-Bromomethyl-3-Nitrobenzoic Acid Succinimide Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under inert conditions when appropriate to maximize shelf-life stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.