Description

4-Chloro-2-Fluoro-5-Hydroxy-Benzoic Acid Methyl Ester is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its multifunctional chemical structure, which allows for selective derivatization at multiple reactive sites. It is primarily sought after by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials.
• Chemical Research: A versatile building block for academic and industrial research in medicinal chemistry, material science, and methodology development.
• Custom Synthesis: Used by fine chemical manufacturers for the contract synthesis of bespoke, complex molecules for client-specific projects.

Basic Information

Product Name	4-Chloro-2-Fluoro-5-Hydroxy-Benzoic Acid Methyl Ester
CAS No.	141852-67-7
Molecular Formula	C8H6ClFO3
Molecular Weight	204.58 g/mol
Synonyms	Methyl 4-Chloro-2-Fluoro-5-Hydroxybenzoate; 5-Hydroxy-4-Chloro-2-Fluorobenzoic Acid Methyl Ester; Benzoic acid, 4-chloro-2-fluoro-5-hydroxy-, methyl ester; Methyl 5-Hydroxy-4-Chloro-2-Fluorobenzoate; 4-Chloro-2-Fluoro-5-hydroxy Methyl Benzoate
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-Fluoro-5-Hydroxy-Benzoic Acid Methyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and specific impurities. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure full traceability and compliance with your project specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.