Description

5-Amino-2-Chloro-4-Fluoro-Benzoic Acid Methyl Ester is a high-purity, multi-functional chemical intermediate of significant importance in advanced organic synthesis. Its molecular structure, featuring distinct amino, chloro, and fluoro substituents, makes it a versatile building block for constructing complex, biologically active molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a critical building block for developing advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Used in the research and production of specialty electronic chemicals for display and lighting technologies.
• Dye & Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and organic pigments.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex heterocyclic compounds and other fine chemicals.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule development projects.

Basic Information

Product Name	5-Amino-2-Chloro-4-Fluoro-Benzoic Acid Methyl Ester
CAS No.	141772-31-8
Molecular Formula	C8H7ClFNO2
Molecular Weight	203.60 g/mol
Synonyms	Methyl 5-Amino-2-Chloro-4-Fluorobenzoate; 2-Chloro-4-Fluoro-5-Aminobenzoic Acid Methyl Ester; Benzoic acid, 5-amino-2-chloro-4-fluoro-, methyl ester; Methyl 5-Amino-2-Chloro-4-Fluorobenzoate; 5-Amino-2-Chloro-4-Fluorobenzoic Acid Methyl Ester; 141772-31-8; Methyl 2-chloro-4-fluoro-5-aminobenzoate
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Chloro-4-Fluoro-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.