Description

5-tert-Butoxycarbonylamino-3-Oxo-Pentanoic Acid Methyl Ester is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex peptide and peptidomimetic structures, offering precise control over molecular architecture. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates and bioactive peptides.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) for the controlled incorporation of specific amino acid sequences.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for amines during complex multi-functional molecule assembly.
• Research & Development: Essential for academic and industrial R&D focused on medicinal chemistry, chemical biology, and new molecular entity (NME) discovery.
• Fine Chemical Production: Employed in the custom synthesis of specialized, high-value compounds for various industrial applications.

Basic Information

Product Name	5-tert-Butoxycarbonylamino-3-Oxo-Pentanoic Acid Methyl Ester
CAS No.	141734-32-9
Molecular Formula	C12H21NO5
Molecular Weight	259.30 g/mol
Synonyms	Boc-Asp(OMe)-OH; Methyl 5-[(tert-butoxycarbonyl)amino]-3-oxopentanoate; Boc-Aspartic Acid β-Methyl Ester; (S)-5-((tert-Butoxycarbonyl)amino)-3-oxopentanoic acid methyl ester; Methyl (S)-5-((tert-butoxycarbonyl)amino)-3-oxopentanoate; Boc-Asp(OMe); N-Boc-L-aspartic acid 4-methyl ester; 3-Oxo-5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our 5-tert-Butoxycarbonylamino-3-Oxo-Pentanoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.