Description

4-(Methylsulfinyl)Phenyl Nitrogen Mustard is a specialized alkylating agent derivative of nitrogen mustard, characterized by the presence of a methylsulfinyl (sulfoxide) functional group. This structural feature is significant for research into targeted drug delivery and the development of novel chemotherapeutic prodrugs. It is primarily utilized by pharmaceutical R&D laboratories and academic institutions engaged in medicinal chemistry and oncology research to study structure-activity relationships and mechanisms of action.

Application

• Medicinal Chemistry Research: A key intermediate for synthesizing and evaluating novel nitrogen mustard-based anticancer prodrugs.
• Oncology Drug Discovery: Used in studies exploring targeted alkylating agents, particularly for their potential selective activation in tumor microenvironments.
• Bioconjugation Studies: Serves as a model compound for developing antibody-drug conjugates (ADCs) or other targeted delivery systems.
• Biochemical Research: Employed as a tool compound to investigate DNA alkylation mechanisms and cellular repair pathways.
• Prodrug Development: The sulfoxide moiety is of interest for designing redox-sensitive prodrugs activated under specific physiological conditions.
• Academic & Institutional Research: Fundamental studies in organic synthesis, chemical biology, and pharmacology.

Basic Information

Product Name	4-(Methylsulfinyl)Phenyl Nitrogen Mustard
CAS No.	141612-08-0
Molecular Formula	C10H14Cl2NOS
Molecular Weight	268.19 g/mol
Synonyms	4-(Methylsulfinyl)phenylbis(2-chloroethyl)amine; p-(Methylsulfinyl)phenyl Nitrogen Mustard; 4-(Methylsulfinyl)-N,N-bis(2-chloroethyl)aniline; 4-(Methylsulfinyl)phenyl Mustard; NSC-Derivative; Sulfoxide Nitrogen Mustard Analog; Research Compound 141612-08-0
EINECS	Contact for details

Quality Control

Our 4-(Methylsulfinyl)Phenyl Nitrogen Mustard is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.