Description

cis-Ethyl 3-(Benzyloxy)Cyclobutanecarboxylate is a high-purity, synthetically valuable cyclobutane derivative. This compound serves as a crucial chiral building block and advanced pharmaceutical intermediate, enabling the synthesis of complex molecules with defined stereochemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides with specific stereochemical requirements for enhanced efficacy.
• Fine Chemical Production: Serves as a versatile precursor for synthesizing complex fragrance compounds, liquid crystals, and other specialty organic materials.
• Academic & Contract Research: Essential reagent for methodological studies in organic synthesis, asymmetric catalysis, and medicinal chemistry research programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	cis-Ethyl 3-(Benzyloxy)Cyclobutanecarboxylate
CAS No.	141352-62-7
Molecular Formula	C14H18O3
Molecular Weight	234.29 g/mol
Synonyms	Ethyl cis-3-(Benzyloxy)cyclobutanecarboxylate; 3-(Benzyloxy)cyclobutanecarboxylic Acid Ethyl Ester (cis-); (1r,3s)-Ethyl 3-(Phenylmethoxy)cyclobutanecarboxylate; (1s,3r)-Ethyl 3-(Benzyloxy)cyclobutanecarboxylate; Cyclobutanecarboxylic acid, 3-(phenylmethoxy)-, ethyl ester, cis-; BOC-Protected Cyclobutane Ester Intermediate; Benzyloxy Cyclobutane Ester
EINECS	Contact for details

Quality Control

Our cis-Ethyl 3-(Benzyloxy)Cyclobutanecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.