Description

2-Furancarboxylic Acid, 5-(Chloroacetyl)Tetrahydro-, Methyl Ester, (2S-Cis)- (9Ci) is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is valued for its specific stereochemistry and functional groups, which are critical for synthesizing complex, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for complex drug candidates.
• Asymmetric Synthesis: Used in stereoselective reactions to construct molecules with defined three-dimensional configurations.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Fine Chemical Manufacturing: Employed in the synthesis of specialty chemicals, agrochemicals, and other high-value compounds requiring precise stereocontrol.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis.

Basic Information

Product Name	2-Furancarboxylic Acid, 5-(Chloroacetyl)Tetrahydro-, Methyl Ester, (2S-Cis)- (9Ci)
CAS No.	141269-24-1
Molecular Formula	C9H11ClO4
Molecular Weight	218.63 g/mol
Synonyms	(2S-cis)-5-(Chloroacetyl)tetrahydro-2-furancarboxylic acid methyl ester; Methyl (2S,5S)-5-(2-chloroacetyl)oxolane-2-carboxylate; Tetrahydro-5-(chloroacetyl)-2-furancarboxylic acid methyl ester, (2S-cis)-; 2-Furancarboxylic acid, 5-(chloroacetyl)tetrahydro-, methyl ester, (2S-cis)-; (2S,5S)-Methyl 5-(2-chloroacetyl)tetrahydrofuran-2-carboxylate; (2S,5S)-5-(Chloroacetyl)tetrahydro-2-furancarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 2-Furancarboxylic Acid, 5-(Chloroacetyl)Tetrahydro-, Methyl Ester, (2S-Cis)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized using advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.