Description

n-Boc-Tryptophan Methyl Ester is a protected derivative of the essential amino acid tryptophan, widely used as a key building block in peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity intermediates to ensure the integrity and yield of complex peptide sequences. It is primarily utilized by the pharmaceutical, biotechnology, and advanced research sectors for the development of therapeutic peptides, peptidomimetics, and other bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a crucial, protected amino acid monomer for the controlled assembly of peptide chains.
• Pharmaceutical Intermediates: Used in the research and production of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation & Labeling: Acts as a precursor for introducing the tryptophan moiety into larger biomolecules for labeling or functionalization studies.
• Academic & Industrial Research: A fundamental reagent in medicinal chemistry and biochemistry labs for studying protein structure-function relationships and designing novel therapeutics.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new biologically active compounds.

Basic Information

Product Name	n-Boc-Tryptophan Methyl Ester
CAS No.	141215-69-2
Molecular Formula	C₁₉H₂₄N₂O₄
Molecular Weight	344.41 g/mol
Synonyms	Boc-Trp-OMe; (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(1H-indol-3-yl)propanoate; tert-Butyloxycarbonyl-tryptophan methyl ester; Boc-L-tryptophan methyl ester; N-α-Boc-L-tryptophan methyl ester; N-(tert-Butoxycarbonyl)-L-tryptophan methyl ester; Methyl N-Boc-L-tryptophanate; L-Tryptophan, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our n-Boc-Tryptophan Methyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as chiral purity, chemical purity, and impurity profiles. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and advanced research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.