Description

1H-Pyrazole-3-Carboxylicacid,1,1-Dimethylethylester(9Ci) is a high-purity pyrazole derivative, a crucial protected intermediate in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the pyrazole core's bioactivity.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers with specific functional properties.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Item	Detail
Product Name	1H-Pyrazole-3-Carboxylicacid,1,1-Dimethylethylester(9Ci)
CAS No.	141178-50-9
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	tert-Butyl 1H-pyrazole-3-carboxylate; 1H-Pyrazole-3-carboxylic acid, 1,1-dimethylethyl ester; 3-(tert-Butoxycarbonyl)-1H-pyrazole; tert-Butyl 3-pyrazolecarboxylate; 1-(tert-Butoxycarbonyl)-1H-pyrazole-3-carboxylic acid (tautomer); Pyrazole-3-carboxylic acid tert-butyl ester; BOC-protected pyrazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazole-3-Carboxylicacid,1,1-Dimethylethylester(9Ci) adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.