Description

(R)-(-)-2-Chlorophenylglycine Methyl Ester CAS NO 141109-16-2 is a high-purity chiral building block and key pharmaceutical intermediate. Its value lies in its specific (R)-configuration, which is critical for synthesizing enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and advanced material sectors, where precise stereochemistry dictates biological activity and material properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Asymmetric Catalysis: Serves as a precursor or ligand in asymmetric synthesis to induce chirality in target molecules.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific optical activity.
• Academic & Industrial R&D: A valuable standard and starting material for method development and research in synthetic organic and medicinal chemistry.
• Peptidomimetics & Bioactive Molecule Construction: Used as a constrained amino acid derivative in the design of novel peptide analogs and enzyme inhibitors.

Basic Information

Product Name	(R)-(-)-2-Chlorophenylglycine Methyl Ester
CAS No.	141109-16-2
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	(R)-2-Chloro-D-phenylglycine methyl ester; Methyl (R)-2-amino-2-(2-chlorophenyl)acetate; (R)-Methyl 2-amino-2-(2-chlorophenyl)acetate; (R)-α-Amino-2-chlorobenzeneacetic acid methyl ester; D-2-Chlorophenylglycine methyl ester; (R)-(-)-Methyl 2-amino-2-(2-chlorophenyl)acetate; (R)-2-Chlorophenylglycine methyl ester
EINECS	Contact for details

Quality Control

Our (R)-(-)-2-Chlorophenylglycine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.