Description

2-Furancarboxylic Acid, 5-(Chloroacetyl)Tetrahydro-, Methyl Ester, (2R-Cis)- (9Ci) is a high-purity chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its value lies in its complex molecular architecture, which incorporates a tetrahydrofuran ring, a chloroacetyl group, and a defined stereocenter, making it a versatile precursor for constructing more complex molecules. This compound is primarily needed by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the specific stereochemistry and functional groups are critical for bioactivity.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce complexity and chirality into target molecules.
• Fine Chemical Production: Acts as a building block for the manufacture of specialty chemicals, flavors, fragrances, or advanced materials requiring specific stereochemical configurations.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for methodological studies and exploring new synthetic pathways.

Basic Information

Product Name	2-Furancarboxylic Acid, 5-(Chloroacetyl)Tetrahydro-, Methyl Ester, (2R-Cis)- (9Ci)
CAS No.	141072-81-3
Molecular Formula	C9H11ClO4
Molecular Weight	218.63 g/mol
Synonyms	(2R,5S)-5-(Chloroacetyl)tetrahydro-2-furancarboxylic acid methyl ester; Methyl (2R,5S)-5-(2-chloroacetyl)tetrahydrofuran-2-carboxylate; (2R-cis)-5-(Chloroacetyl)tetrahydro-2-furancarboxylic Acid Methyl Ester; Tetrahydro-5-(chloroacetyl)-2-furancarboxylic acid methyl ester, (2R-cis)-; 141072-81-3; (2R,5S)-rel-5-(Chloroacetyl)tetrahydro-2-furancarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 2-Furancarboxylic Acid, 5-(Chloroacetyl)Tetrahydro-, Methyl Ester, (2R-Cis)- (9Ci) is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity. For long-term storage, consider using desiccants and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.