Description

Matlystatin E is a potent and specific inhibitor of matrix metalloproteinases (MMPs), a class of enzymes critical in tissue remodeling and disease progression. This compound is valued in research for its ability to precisely modulate extracellular matrix degradation, providing key insights into pathological processes. It serves as an essential biochemical tool for pharmaceutical R&D, academic research, and biotechnology applications focused on cancer metastasis, arthritis, and cardiovascular diseases.

Application

• Biochemical Research: Used as a selective inhibitor to study the function and inhibition mechanisms of specific matrix metalloproteinases (MMPs) in vitro.
• Pharmaceutical Development: Acts as a reference standard and lead compound in the discovery of novel therapeutics targeting conditions like tumor invasion, metastasis, and angiogenesis.
• Disease Mechanism Studies: Employed in cellular and animal models to investigate the role of MMPs in inflammatory diseases, including rheumatoid arthritis and atherosclerosis.
• Enzyme Profiling & Screening: Utilized in high-throughput screening assays to identify and characterize new MMP inhibitors for drug discovery pipelines.
• Academic Research: Serves as a critical reagent in university laboratories for fundamental studies on extracellular matrix biology and protease regulation.

Basic Information

Product Name	Matlystatin E
CAS No.	140638-26-2
Molecular Formula	C34H62N4O8
Molecular Weight	654.89 g/mol
Synonyms	Matlystatin E; NSC 339578; MMP Inhibitor Matlystatin E; (2S)-2-[(2S,3S)-3-[(2S)-2-[(2S,3S)-3-[(2S)-2-Acetamido-3-phenylpropanamido]-2-hydroxybutanamido]-3-phenylpropanamido]-2-hydroxybutanamido]-N-[(1S,2R)-1-hydroxy-2-methyl-4-(methylsulfanyl)butyl]pentanediamide
EINECS	Contact for details

Quality Control

Every batch of Matlystatin E is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including HPLC for purity and spectroscopic methods for structural confirmation, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.