Description

5-Azido-3-o-Benzoyl-6-o-tert-Butyldiphenylsilyl-5-Deoxy-1,2-o-Isopropylidene Talofuranose is a sophisticated, multi-functionalized carbohydrate derivative, specifically a protected talofuranose sugar, designed for advanced synthetic chemistry. This compound is a critical high-purity building block for the synthesis of complex nucleoside analogues and other biologically active molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel therapeutics and diagnostic agents.

Application

• Nucleoside Analogue Synthesis: A key protected intermediate for constructing modified nucleosides with potential antiviral or anticancer activity.
• Pharmaceutical Research: Serves as a versatile scaffold in medicinal chemistry for probing structure-activity relationships (SAR) and developing new active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry: Used in the study and synthesis of complex oligosaccharides and glycoconjugates due to its selectively protected functional groups.
• Bioconjugation & Probe Development: The azido group enables efficient "click chemistry" (e.g., CuAAC) for labeling, tagging, and creating molecular probes.
• Process Chemistry Development: Employed in scaling up synthetic routes for novel compounds in pilot plants and commercial manufacturing.
• Academic & Institutional Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and chemical biology.

Basic Information

Product Name	5-Azido-3-o-Benzoyl-6-o-tert-Butyldiphenylsilyl-5-Deoxy-1,2-o-Isopropylidene Talofuranose
CAS No.	140451-85-0
Molecular Formula	C37H39N3O6Si
Molecular Weight	637.82 g/mol
Synonyms	1,2-O-Isopropylidene-5-azido-3-O-benzoyl-6-O-(tert-butyldiphenylsilyl)-5-deoxy-α-D-talofuranose; 5-Azido-5-deoxy-1,2-O-isopropylidene-3-O-benzoyl-6-O-(tert-butyldiphenylsilyl)-α-D-talofuranose; 5-Azido-3-O-benzoyl-6-O-TBDPS-5-deoxy-1,2-O-isopropylidene-α-D-talofuranose; Protected 5-Azidotalofuranose Derivative; TBDPS-Protected Azido Talofuranose Intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC, NMR, and mass spectrometry to verify identity and purity. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our quality management system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as specified on the label or Certificate of Analysis. This compound is strictly light-sensitive and must be protected from all light exposure. Keep container tightly sealed in a dry, well-ventilated place. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.