Description

2-Azidoethyl 2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranoside is a key protected glycosyl donor and intermediate in synthetic carbohydrate chemistry. This compound is specifically designed for the efficient construction of complex oligosaccharides and glycoconjugates, offering a reactive azidoethyl linker for subsequent functionalization via click chemistry. It is an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors developing novel glycotherapeutics, vaccines, and targeted delivery systems.

Application

• Glycoconjugate Synthesis: A critical precursor for the preparation of neoglycoconjugates, glycoproteins, and glycolipids via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Oligosaccharide Assembly: Serves as a versatile mannosyl donor in automated and solution-phase oligosaccharide synthesis for creating biologically active carbohydrate structures.
• Pharmaceutical Research: Used in the development of carbohydrate-based vaccines, antiviral agents, and drug delivery vehicles that target specific lectin receptors.
• Diagnostic Probe Development: Enables the labeling of biomolecules with carbohydrate motifs for use in imaging, biosensing, and cellular targeting studies.
• Material Science: Facilitates the surface functionalization of polymers, nanoparticles, and chips with bioactive sugar moieties for creating advanced biomaterials.
• Chemical Biology Tools: Employed to synthesize activity-based probes for studying glycosidase enzymes and carbohydrate-mediated biological processes.

Basic Information

Product Name	2-Azidoethyl 2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranoside
CAS No.	140428-83-7
Molecular Formula	C16H23N3O10
Molecular Weight	417.37 g/mol
Synonyms	2-Azidoethyl 2,3,4,6-Tetra-O-acetyl-α-D-mannopyranoside; α-D-Mannopyranoside, 2-azidoethyl 2,3,4,6-tetra-O-acetate; 2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl azidoethyl ether; Ac4Manα-O-(CH2)2N3; Protected Mannosyl Azide; Mannose Azidoethyl Glycoside, peracetylated
EINECS	Contact for details

Quality Control

Our 2-Azidoethyl 2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranoside is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and optical rotation for stereochemical integrity, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) with full characterization data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.