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2-Azidoethyl 2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranoside CAS NO 140428-81-5


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CAS No.:140428-81-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Azidoethyl 2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranoside is a key protected glycosyl donor and intermediate in carbohydrate chemistry. This compound matters for its role in the efficient synthesis of complex oligosaccharides and glycoconjugates via click chemistry and other bioorthogonal reactions. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for developing novel glycotherapeutics, vaccines, and molecular probes.

Application

  • Glycoconjugate Synthesis: A crucial building block for creating neoglycoconjugates, glycoproteins, and glycolipids via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
  • Pharmaceutical Intermediates: Serves as a protected intermediate in the synthesis of glycosidase inhibitors, antiviral agents, and other bioactive carbohydrate-based drugs.
  • Chemical Biology Probes: Used to label biomolecules with carbohydrate tags for studying glycan-protein interactions, cell surface engineering, and metabolic labeling.
  • Vaccine Development: Employed in the research and production of carbohydrate-based vaccines, including conjugate vaccines targeting bacterial pathogens.
  • Material Science: Facilitates the surface functionalization of polymers and nanoparticles with sugar moieties to create bioactive materials.
  • Enzyme Substrate Studies: Acts as a substrate or inhibitor in enzymatic assays for glycosyltransferases and glycosidases.

Basic Information

Product Name 2-Azidoethyl 2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranoside
CAS No. 140428-81-5
Molecular Formula C₁₆H₂₃N₃O₁₀
Molecular Weight 417.37 g/mol
Synonyms 2-Azidoethyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside; β-D-Glucopyranoside, 2-azidoethyl 2,3,4,6-tetra-O-acetyl-; 2-Azidoethyl tetra-O-acetyl-β-D-glucopyranoside; Ac₄Glcβ-O-(CH₂)₂N₃; Tetraacetylated Azidoethyl Glucoside; 1,2,3,4,6-Penta-O-acetyl-β-D-glucopyranose Azidoethyl Derivative; Azidoethyl Glucoside Tetraacetate; N₃(CH₂)₂O-Glc(Ac)₄
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Quality Control

Our 2-Azidoethyl 2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranoside is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere at lower temperatures (-20°C) to maintain optimal stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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