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(3R,4R)-(-)-3,4-Diazido-1-(Phenylmethyl)Pyrrolidine CAS NO 140134-20-9


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CAS No.:140134-20-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(3R,4R)-(-)-3,4-Diazido-1-(Phenylmethyl)Pyrrolidine is a high-value, chiral diazido pyrrolidine derivative that serves as a critical synthetic intermediate. This compound matters for its role in facilitating stereoselective synthesis, particularly in the construction of complex nitrogen-containing heterocycles and chiral ligands. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

  • Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, including protease inhibitors and other biologically active molecules.
  • Agrochemical Synthesis: Used in the research and development of stereochemically defined pesticides and herbicides.
  • Ligand and Catalyst Preparation: Serves as a precursor for the development of chiral ligands used in asymmetric catalysis.
  • Material Science Research: Employed in the synthesis of specialized polymers and advanced materials with tailored properties.
  • Click Chemistry Substrate: The azido groups make it a valuable substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions in bioconjugation and polymer chemistry.
  • Academic and R&D Laboratories: Essential for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Item Detail
Product Name (3R,4R)-(-)-3,4-Diazido-1-(Phenylmethyl)Pyrrolidine
CAS No. 140134-20-9
Molecular Formula C11H13N7
Molecular Weight 243.27 g/mol
Synonyms (3R,4R)-3,4-Diazido-1-benzylpyrrolidine; (-)-1-Benzyl-3,4-diazidopyrrolidine; (3R,4R)-1-Benzyl-3,4-diazidopyrrolidine; 1-Benzyl-(3R,4R)-3,4-diazidopyrrolidine; (3R,4R)-1-(Phenylmethyl)-3,4-diazidopyrrolidine; 3,4-Diazido-1-benzylpyrrolidine (enantiomer); 140134-20-9
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Quality Control

Our (3R,4R)-(-)-3,4-Diazido-1-(Phenylmethyl)Pyrrolidine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Keep away from heat, sparks, open flames, and incompatible materials. Due to the presence of azido groups, handle and store only in small quantities appropriate for immediate use.

Specification

Item Specification
Appearance Colorless to pale yellow liquid or low-melting solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Enantiomeric Excess (Chiral HPLC) ≥ 98% ee
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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