Description

Cyclobutanecarboxylic Acid, 2-(1-Methylethenyl)-, Methyl Ester, (1S-Cis)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique cyclobutane core and functional groups make it a valuable intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides where specific stereochemistry is crucial for biological activity.
• Fine Chemical Production: Serves as a specialized building block in the synthesis of complex fragrances, flavors, and other high-value specialty chemicals.
• Academic & Industrial Research: Employed in methodological studies and process chemistry for developing new synthetic routes involving strained ring systems.
• Material Science Precursor: Potential use in the synthesis of monomers for specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 2-(1-Methylethenyl)-, Methyl Ester, (1S-Cis)- (9Ci)
CAS No.	139561-15-2
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1S-cis)-2-Isopropenylcyclobutanecarboxylic acid methyl ester; Methyl (1S,2S)-2-isopropenylcyclobutanecarboxylate; (1S,2S)-2-(Prop-1-en-2-yl)cyclobutanecarboxylic acid methyl ester; 2-Isopropenylcyclobutanecarboxylic acid methyl ester, (1S-cis)-; (1S,2S)-2-Vinylcyclobutanecarboxylic acid methyl ester (related); Chiral cyclobutane ester; (1S,2S)-2-(1-Methylethenyl)cyclobutanecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Cyclobutanecarboxylic Acid, 2-(1-Methylethenyl)-, Methyl Ester, (1S-Cis)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.