Description

1,4-Dioxa-7-Aza-Spiro[4.4]Nonane-7-Carboxylic Acid Benzyl Ester is a sophisticated spirocyclic building block of significant value in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex pharmaceutical molecules and fine chemicals, offering a rigid, heterocyclic scaffold. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring spirocyclic or constrained heterocyclic motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where its unique structure can impart specific biological activity.
• Ligand and Catalyst Development: Employed as a starting material for creating specialized chelating ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Acts as a monomer or functional additive in the development of advanced polymers with tailored properties.
• Academic & Industrial R&D: A valuable tool for methodological studies and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	1,4-Dioxa-7-Aza-Spiro[4.4]Nonane-7-Carboxylic Acid Benzyl Ester
CAS No.	139524-57-5
Molecular Formula	C14H17NO4
Molecular Weight	263.29 g/mol
Synonyms	7-(Benzyloxycarbonyl)-1,4-dioxa-7-azaspiro[4.4]nonane; Benzyl 1,4-dioxa-7-azaspiro[4.4]nonane-7-carboxylate; 7-Cbz-1,4-dioxa-7-azaspiro[4.4]nonane; 1,4-Dioxa-7-azaspiro[4.4]nonane-7-carboxylic acid phenylmethyl ester; Spirocyclic Cbz-protected amino acetal
EINECS	Contact for details

Quality Control

Our 1,4-Dioxa-7-Aza-Spiro[4.4]Nonane-7-Carboxylic Acid Benzyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.