Description

4-Azido-2,3,5,6-Tetrafluorobenzyl Amine Hydrochloride is a specialized, high-value fluorinated aromatic building block containing a reactive azido group. This compound is critical for advanced organic synthesis, particularly in click chemistry applications for bioconjugation and materials science. It is primarily utilized by research institutions and pharmaceutical companies developing novel drug candidates, diagnostic agents, and functional polymers.

Application

• Click Chemistry Reagent: A key precursor for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create triazole linkages in bioconjugates.
• Pharmaceutical Intermediate: Used in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and potential PET (Positron Emission Tomography) imaging agents.
• Bioconjugation: Enables site-specific labeling of proteins, antibodies, and oligonucleotides with fluorophores, drugs, or other functional molecules.
• Materials Science: Serves as a monomer or cross-linker for synthesizing advanced polymers with unique surface properties or for creating functionalized surfaces.
• Agrochemical Research: Employed in the development of novel fluorinated herbicides, pesticides, and plant growth regulators.
• Chemical Biology Probes: Used to create activity-based probes for studying enzyme function and metabolic pathways.

Basic Information

Product Name	4-Azido-2,3,5,6-Tetrafluorobenzyl Amine Hydrochloride
CAS No.	139428-47-0
Molecular Formula	C7H4ClF4N4
Molecular Weight	256.58 g/mol
Synonyms	4-Azido-2,3,5,6-tetrafluorobenzylamine hydrochloride; 2,3,5,6-Tetrafluoro-4-azidobenzylamine hydrochloride; (4-Azido-2,3,5,6-tetrafluorophenyl)methanamine hydrochloride; 4-Azidotetrafluorobenzylamine HCl; 4-Azido-α,α,α,α-tetrafluorotoluene-amine hydrochloride; 139428-47-0; 4-Azido-2,3,5,6-tetrafluorobenzylazanium chloride
EINECS	Contact for details

Quality Control

Our 4-Azido-2,3,5,6-Tetrafluorobenzyl Amine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under an inert atmosphere. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.