Description

1-Aza-2,5-Disilacyclopentane-1-Acetic Acid, -α-,2,2,5,5-Pentamethyl-, Phenylmethyl Ester, (S)- (9Ci) is a high-value, chiral organosilicon compound with a unique heterocyclic structure, serving as a critical advanced intermediate in sophisticated organic synthesis. Its precise stereochemistry and functional groups make it indispensable for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialty materials. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce silicon-containing motifs or chiral centers with high selectivity.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting protease inhibitors or other biologically active molecules.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides where the silacyclopentane scaffold can impart unique biological activity and stability.
• Organometallic Catalyst Ligand Precursor: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and cross-coupling reactions.
• Advanced Material Research: Employed in the development of silicon-based polymers, dendrimers, or hybrid organic-inorganic materials with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, exploring new C-Si bond formation strategies and heterocyclic chemistry.

Basic Information

Product Name	1-Aza-2,5-Disilacyclopentane-1-Acetic Acid, -α-,2,2,5,5-Pentamethyl-, Phenylmethyl Ester, (S)- (9Ci)
CAS No.	139215-48-8
Molecular Formula	C17H29NO2Si2
Molecular Weight	335.60 g/mol
Synonyms	(S)-Benzyl 2-(2,2,5,5-tetramethyl-1-phenyl-1-aza-2,5-disilacyclopent-1-yl)acetate; Benzyl (S)-2-(2,2,5,5-tetramethyl-1-phenyl-1-aza-2,5-disilacyclopentan-1-yl)acetate; 1-Aza-2,5-disilacyclopentane-1-acetic acid, α,2,2,5,5-pentamethyl-, phenylmethyl ester, (S)-; (S)-α,2,2,5,5-Pentamethyl-1-aza-2,5-disilacyclopentane-1-acetic acid phenylmethyl ester
EINECS	Contact for details

Quality Control

Every batch of our 1-Aza-2,5-Disilacyclopentane-1-Acetic Acid, -α-,2,2,5,5-Pentamethyl-, Phenylmethyl Ester, (S)- (9Ci) is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity, meeting the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.