Description

2-Fluoro-4-Iodophenyl Isocyanate 95 is a halogenated aromatic isocyanate building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for introducing the 2-fluoro-4-iodophenyl moiety into target molecules via urea or carbamate linkages.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the fluorine and iodine substituents can modulate biological activity and stability.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialized polymers, polyurethanes, and coatings with unique properties.
• Chemical Biology & Proteomics: Employed in the design of activity-based probes (ABPs) and affinity labels for studying enzyme function and protein profiling.
• Ligand & Catalyst Development: Utilized to create sophisticated ligands for catalysis or metal-organic frameworks (MOFs) with tailored functionalities.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Fluoro-4-Iodophenyl Isocyanate 95
CAS No.	139072-17-6
Molecular Formula	C7H3FINO
Molecular Weight	278.99 g/mol
Synonyms	4-Iodo-2-fluorophenyl isocyanate; 2-Fluoro-4-iodobenzene isocyanate; Isocyanic acid, 2-fluoro-4-iodophenyl ester; 1-Fluoro-2-isocyanato-4-iodobenzene; (2-Fluoro-4-iodophenyl)isocyanate
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Iodophenyl Isocyanate 95 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the specified standard of ≥95% purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture. Keep away from heat, open flames, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.