Description

Pyridine, 1-(2-Bromo-1-Oxo-2-Propenyl)-1,2,3,6-Tetrahydro- (9Ci) CAS NO 139021-47-9 is a specialized heterocyclic building block featuring a reactive bromoacryloyl moiety tethered to a partially saturated pyridine ring. This unique molecular architecture makes it a versatile intermediate for synthesizing complex pharmacologically active compounds and advanced materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammation.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a precursor for creating complex chelating ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, photoactive polymers, and other advanced functional materials.
• Chemical Biology Probes: Useful for synthesizing activity-based probes and molecular tags for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	Pyridine, 1-(2-Bromo-1-Oxo-2-Propenyl)-1,2,3,6-Tetrahydro- (9Ci)
CAS No.	139021-47-9
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	1-(2-Bromoacryloyl)-1,2,3,6-tetrahydropyridine; 2-Bromo-1-(1,2,3,6-tetrahydro-1-pyridinyl)-1-propen-1-one; 1-(2-Bromo-1-oxo-2-propen-1-yl)-1,2,3,6-tetrahydropyridine; 1-(2-Bromoacryloyl)-1,2,3,6-tetrahydropyridine; 1-(2-Bromoacryloyl)-1,2,3,6-tetrahydropyridine; 1-(2-Bromoacryloyl)-1,2,3,6-tetrahydropyridine; 1-(2-Bromoacryloyl)-1,2,3,6-tetrahydropyridine; 1-(2-Bromoacryloyl)-1,2,3,6-tetrahydropyridine
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Quality Control

Our Pyridine, 1-(2-Bromo-1-Oxo-2-Propenyl)-1,2,3,6-Tetrahydro- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP and ISO 9001 compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.