Description

L-Threo-Hexuronic Acid, 2,3-Anhydro-4,5-Dideoxy-, Methyl Ester (9Ci) is a specialized anhydro sugar derivative, a key chiral building block in advanced organic synthesis. Its unique, rigid bicyclic structure makes it a valuable precursor for synthesizing complex nucleoside analogs, carbohydrate-based pharmaceuticals, and other bioactive molecules. This high-purity intermediate is essential for research and development in pharmaceutical chemistry, agrochemical discovery, and fine chemical manufacturing where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the development of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Agrochemical Synthesis: Used as a building block for creating stereochemically defined active ingredients in advanced crop protection agents.
• Fine Chemical Production: Serves as a starting material for the synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Glycochemistry Research: An important tool in academic and industrial research for studying carbohydrate chemistry and developing new glycosylation methodologies.
• Diagnostic Reagent Development: Potential use in the synthesis of labeled compounds or probes for biochemical assays and diagnostic applications.
• Material Science Precursor: Can be utilized in the development of novel polymers or functional materials with specific chiral properties.

Basic Information

Item	Details
Product Name	L-Threo-Hexuronic Acid, 2,3-Anhydro-4,5-Dideoxy-, Methyl Ester (9Ci)
CAS No.	138876-73-0
Molecular Formula	C7H10O5
Molecular Weight	174.15 g/mol
Synonyms	Methyl 2,3-anhydro-4,5-dideoxy-L-threo-hexuronate; 2,3-Anhydro-4,5-dideoxy-L-threo-hexuronic acid methyl ester; L-threo-Hexuronic acid, 2,3-anhydro-4,5-dideoxy-, methyl ester; Methyl (3aS,5R,6S,6aR)-5-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-6-carboxylate (related structure); Anhydro sugar methyl ester; L-threo-Hexuronate derivative
EINECS	Contact for details

Quality Control

Our L-Threo-Hexuronic Acid, 2,3-Anhydro-4,5-Dideoxy-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.