Description

4-Bis(Trimethylsilyl)Methylpyridine is a specialized organosilicon compound featuring a pyridine core flanked by two trimethylsilylmethyl groups. This unique structure makes it a valuable silyl-protecting group precursor and a versatile building block in advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of complex drug molecules, particularly those requiring silicon incorporation for enhanced metabolic stability or lipophilicity.
• Agrochemical Research: Used as a building block for creating novel pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Acts as a precursor for silicon-containing polymers, coatings, and advanced materials with specific thermal or surface properties.
• Organic Synthesis Reagent: Functions as a versatile reagent for introducing the bulky bis(trimethylsilyl)methyl group, useful for steric protection and modulating electronic properties in target molecules.
• Ligand Synthesis: Employed in the preparation of novel ligands for catalysis, including those used in asymmetric synthesis and cross-coupling reactions.
• Chemical Research & Development: A valuable tool for exploring new synthetic methodologies and reaction pathways in academic and industrial R&D laboratories.

Basic Information

Item	Details
Product Name	4-Bis(Trimethylsilyl)Methylpyridine
CAS No.	138761-45-2
Molecular Formula	C13H25NSi2
Molecular Weight	251.52 g/mol
Synonyms	4-[(Trimethylsilyl)methyl]-α-(trimethylsilyl)methylpyridine; 4-(Bis(trimethylsilyl)methyl)pyridine; Pyridine, 4-[(trimethylsilyl)methyl]-α-(trimethylsilyl)methyl-; 4-(Di(trimethylsilyl)methyl)pyridine; 4-Pyridylbis(trimethylsilyl)methane
EINECS	Contact for details

Quality Control

Every batch of 4-Bis(Trimethylsilyl)Methylpyridine is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our quality control includes comprehensive analytical testing via HPLC, GC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.