Description

1-(tert-Butyl)3-Methylbicyclo[1.1.1]pentane-1,3-dicarboxylate is a high-purity, synthetically valuable bicyclic building block. This compound is a critical intermediate in advanced organic synthesis, prized for its rigid, three-dimensional scaffold which imparts unique steric and electronic properties to target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for creating conformationally restricted analogs.
• Agrochemical Synthesis: Used in the design and synthesis of novel pesticides and herbicides, where its bicyclic structure can enhance biological activity and stability.
• Material Science Research: Acts as a precursor for specialty polymers and advanced organic frameworks (MOFs/COFs) requiring specific geometric constraints.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful in constructing molecular probes and tags for studying biological systems due to its robust and modifiable structure.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new chemical space in synthetic organic chemistry laboratories.

Basic Information

Product Name	1-(tert-Butyl)3-Methylbicyclo[1.1.1]pentane-1,3-dicarboxylate
CAS No.	138732-31-7
Molecular Formula	C14H22O4
Molecular Weight	254.32 g/mol
Synonyms	1-(tert-Butyl) 3-methyl bicyclo[1.1.1]pentane-1,3-dicarboxylate; tert-Butyl 3-methylbicyclo[1.1.1]pentane-1-carboxylate 3-carboxylate; 1,3-Bicyclo[1.1.1]pentanedicarboxylic acid, 1-(1,1-dimethylethyl) 3-methyl ester; Bicyclo[1.1.1]pentane-1,3-dicarboxylic acid, 1-tert-butyl 3-methyl ester; BCP ester derivative; [1.1.1]Propellane dicarboxylate derivative
EINECS	Contact for details

Quality Control

Our 1-(tert-Butyl)3-Methylbicyclo[1.1.1]pentane-1,3-dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.