Description

5-(2,5-Difluorophenyl)Isoxazole is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates both a difluorophenyl moiety and an isoxazole ring, making it a versatile precursor for constructing complex pharmacophores. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a core scaffold for developing new generations of herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Precursor: Used in the research and development of advanced organic electronic materials, such as OLEDs and semiconductors, due to its fluorinated aromatic system.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	5-(2,5-Difluorophenyl)Isoxazole
CAS No.	138716-47-9
Molecular Formula	C9H5F2NO
Molecular Weight	181.14 g/mol
Synonyms	5-(2,5-Difluorophenyl)-1,2-oxazole; 5-(2,5-Difluorophenyl)-isoxazole; 2,5-Difluorophenylisoxazole; Isoxazole, 5-(2,5-difluorophenyl)-; 138716-47-9; AKOS005158889
EINECS	Contact for details

Quality Control

Every batch of 5-(2,5-Difluorophenyl)Isoxazole is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.