Description

tert-Butyl 4-(4-Fluorophenyl)-5,6-dihydropyridine-1(2H)-carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of novel therapeutic agents. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications in medicinal chemistry and process development.

Application

• Key Intermediate in API Synthesis: A crucial precursor in the multi-step synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used extensively in research and development for structure-activity relationship (SAR) studies and the creation of new chemical entities.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for cost-effective and robust manufacturing processes.
• Building Block for Heterocyclic Compounds: Its dihydropyridine core is a versatile scaffold for constructing a wide range of biologically active heterocycles.

Basic Information

Product Name	tert-Butyl 4-(4-Fluorophenyl)-5,6-dihydropyridine-1(2H)-carboxylate
CAS No.	138647-52-6
Molecular Formula	C16H20FNO2
Molecular Weight	277.34 g/mol
Synonyms	1-Boc-4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridine; 4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridine-1-carboxylate; 1-N-Boc-4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridine; 4-(p-Fluorophenyl)-1,2,3,6-tetrahydropyridine-1-carboxylic acid tert-butyl ester; 138647-52-6; 1,2,3,6-Tetrahydro-4-(4-fluorophenyl)pyridine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Fluorophenyl)-5,6-dihydropyridine-1(2H)-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.