Description

2-(4-Fluorophenyl)-Propanedioic Acid, 1,3-Mdiethyl Ester is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound serves as a versatile intermediate, enabling the efficient construction of complex molecular architectures for research and development. It is primarily utilized by pharmaceutical, agrochemical, and advanced material scientists seeking to incorporate fluorinated phenyl motifs into target molecules to modulate their biological activity and physical properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs) with potential therapeutic applications.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides where the fluorophenyl group enhances bioactivity and stability.
• Material Science Precursor: Serves as a monomer or building block for specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Synthesis: A versatile reagent for Knoevenagel condensations and other C-C bond-forming reactions in fine chemical production.
• Academic & Industrial R&D: Essential for exploratory chemistry in universities and corporate research laboratories focusing on fluoroorganic chemistry.

Basic Information

Product Name	2-(4-Fluorophenyl)-Propanedioic Acid, 1,3-Mdiethyl Ester
CAS No.	138485-30-0
Molecular Formula	C₁₃H₁₅FO₄
Molecular Weight	254.26 g/mol
Synonyms	Diethyl 2-(4-fluorophenyl)malonate; 2-(4-Fluorophenyl)malonic Acid Diethyl Ester; Diethyl (4-fluorophenyl)malonate; Propanedioic acid, 2-(4-fluorophenyl)-, 1,3-diethyl ester; 1,3-Diethyl 2-(4-fluorophenyl)propanedioate; 4-Fluorophenylmalonic Acid Diethyl Ester; (4-Fluorophenyl)malonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-Propanedioic Acid, 1,3-Mdiethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.