Description

(2R,3R)-Rel-1,2,3,4-Butanetetracarboxylic Acid, 2,3-Dimethyl Ester is a high-purity, stereochemically defined diester derivative of butanetetracarboxylic acid. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, offering precise molecular geometry for the development of complex molecules. It is essential for research and production in the pharmaceutical, agrochemical, and specialty polymer industries, where stereochemical control is paramount for product efficacy and performance.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs requiring specific stereochemistry for biological activity.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides, where the defined (2R,3R) configuration can influence biological targeting and environmental persistence.
• Ligand and Catalyst Preparation: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity in chemical reactions.
• Specialty Polymer Monomer: Acts as a monomer or cross-linking agent for synthesizing polymers with specific tacticity, thermal properties, or biodegradability profiles.
• Fine Chemical Production: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances that demand high stereochemical purity.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and for studying structure-activity relationships (SAR) in new chemical entities.

Basic Information

Product Name	(2R,3R)-Rel-1,2,3,4-Butanetetracarboxylic Acid, 2,3-Dimethyl Ester
CAS No.	138405-05-7
Molecular Formula	C10H14O8
Molecular Weight	262.21 g/mol
Synonyms	(2R,3R)-2,3-Dimethyl 1,2,3,4-butanetetracarboxylate; (2R,3R)-Dimethyl Butane-1,2,3,4-tetracarboxylate; (2R,3R)-1,2,3,4-Butanetetracarboxylic Acid Dimethyl Ester; (2R,3R)-BTCA Dimethyl Ester; (2R,3R)-rel-1,2,3,4-Butanetetracarboxylic Acid 2,3-Dimethyl Ester; (2R,3R)-Tetramethoxycarbonylbutane; (2R,3R)-Dimethyl Oxybis(propanedioate)
EINECS	Contact for details

Quality Control

Our (2R,3R)-Rel-1,2,3,4-Butanetetracarboxylic Acid, 2,3-Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is stable under these conditions. Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (2R,3R)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.