Description

Methyl-(2-Oxo-2-Phenyl-Ethyl)-Carbamic Acid tert-Butyl Ester is a high-value, protected amino acid derivative and a crucial synthetic intermediate in advanced organic chemistry. Its primary value lies in its role as a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Peptidomimetic Synthesis: Used to incorporate modified amino acid residues into peptide chains to enhance stability, bioavailability, and biological activity.
• Protecting Group Chemistry: The tert-butyloxycarbonyl (Boc) group provides orthogonal protection for amines in multi-step synthetic sequences.
• Agrochemical Research: Serves as a building block for developing new active ingredients in crop protection products.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new chemical entities and synthetic pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for cGMP and non-GMP production of specified target molecules for clients.

Basic Information

Product Name	Methyl-(2-Oxo-2-Phenyl-Ethyl)-Carbamic Acid tert-Butyl Ester
CAS No.	138371-45-6
Molecular Formula	C14H19NO3
Molecular Weight	249.31 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-2-aminoacetophenone; Boc-Aminoacetophenone; 2-((tert-Butoxycarbonyl)amino)-1-phenylethan-1-one; N-Boc-2-aminoacetophenone; tert-Butyl (2-oxo-2-phenylethyl)carbamate; (2-Oxo-2-phenylethyl)carbamic acid tert-butyl ester; Boc-APA; N-(tert-Butyloxycarbonyl)-2-aminoacetophenone
EINECS	Contact for details

Quality Control

Our Methyl-(2-Oxo-2-Phenyl-Ethyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment. Our quality commitment supports applications from research to development and commercial scale, adhering to relevant ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥98.5%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.