Description

R-Cyclopropylglycine Methyl Ester Hydrochloride is a high-purity chiral building block essential for advanced pharmaceutical synthesis. This compound is valued for its role in introducing the constrained cyclopropyl moiety into target molecules, which can enhance metabolic stability and binding affinity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents.
• Peptidomimetic Synthesis: Used to incorporate the cyclopropylglycine unit into peptide backbones to modify biological activity and stability.
• API Development: Serves as a critical building block in the synthesis of complex active pharmaceutical ingredients, particularly in oncology and neurology.
• Asymmetric Synthesis: Employed in stereoselective chemical reactions to construct molecules with defined chiral centers.
• Chemical Biology Research: Utilized as a probe or tool compound to study enzyme mechanisms and protein-ligand interactions.
• Process Chemistry: Applied in scale-up and optimization of manufacturing routes for candidate drugs.

Basic Information

Product Name	R-Cyclopropylglycine Methyl Ester Hydrochloride
CAS No.	138326-69-9
Molecular Formula	C7H12ClNO2
Molecular Weight	177.63 g/mol
Synonyms	(R)-2-Amino-2-cyclopropylacetic acid methyl ester hydrochloride; Methyl (R)-2-amino-2-cyclopropylacetate hydrochloride; (R)-Cyclopropylglycine methyl ester HCl; (R)-Aminocyclopropanecarboxylic acid methyl ester hydrochloride; (R)-Methyl 2-amino-2-cyclopropylacetate hydrochloride; (R)-ACPC methyl ester hydrochloride; (R)-2-Cyclopropylglycine methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our R-Cyclopropylglycine Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.