Description

Trimethyl((4-Pentylphenyl)Ethynyl)Silane is a specialized organosilicon compound featuring a phenylacetylene core functionalized with a pentyl chain and a trimethylsilyl protecting group. This molecular architecture makes it a valuable advanced intermediate in organic synthesis, particularly for constructing complex conjugated systems. It is primarily utilized by pharmaceutical, agrochemical, and materials science research and development teams for applications requiring precise molecular assembly.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those with arylacetylene motifs.
• Agrochemical Synthesis: Used in the research and development of novel crop protection agents and herbicides.
• Organic Electronic Materials: Acts as a precursor for the development of organic semiconductors, liquid crystals, and other functional materials requiring conjugated molecular backbones.
• Cross-Coupling Reactions: An effective substrate in Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions to form complex carbon-carbon bonds.
• Chemical Research: Employed in academic and industrial R&D laboratories for exploring new synthetic methodologies and creating novel molecular structures.
• Polymer Modification: Can be used to introduce functional silane groups into polymer chains, modifying their properties.

Basic Information

Product Name	Trimethyl((4-Pentylphenyl)Ethynyl)Silane
CAS No.	138220-08-3
Molecular Formula	C₁₆H₂₄Si
Molecular Weight	244.45 g/mol
Synonyms	((4-Pentylphenyl)ethynyl)trimethylsilane; Trimethyl(4-pentylphenylethynyl)silane; 1-Trimethylsilyl-2-(4-pentylphenyl)acetylene; 4-Pentylphenylacetylene trimethylsilyl derivative; TMS-protected 4-pentylphenylacetylene; (4-Amylphenylethynyl)trimethylsilane; Silane, trimethyl[(4-pentylphenyl)ethynyl]-
EINECS	Contact for details

Quality Control

Our Trimethyl((4-Pentylphenyl)Ethynyl)Silane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for advanced intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to ensure product stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.