Description

cis-Diamminebis(O(6),9-Dimethylguanine-7)Platinum(II) is a specialized organoplatinum coordination complex with significant research and development potential in advanced pharmaceutical chemistry. This compound matters for its role as a sophisticated precursor or active pharmaceutical ingredient (API) intermediate in the development of next-generation platinum-based anticancer agents. Pharmaceutical R&D laboratories, academic institutions, and fine chemical manufacturers focused on oncology drug discovery are the primary users seeking this high-value material.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel platinum-based chemotherapeutic agents targeting specific DNA bases.
• Oncology Drug Discovery: Used in biochemical assays and preclinical studies to investigate structure-activity relationships (SAR) and mechanisms of action against cancer cell lines.
• Chemical Biology Studies: Employed as a molecular probe to study platinum-guanine interactions and DNA adduct formation for understanding drug resistance and toxicity profiles.
• Fine Chemical Synthesis: Serves as a building block for creating more complex, targeted platinum complexes with modified pharmacological properties.
• Academic Research: Utilized in universities and research institutes for fundamental studies in bioinorganic chemistry and metallodrug design.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in related API manufacturing.

Basic Information

Product Name	cis-Diamminebis(O(6),9-Dimethylguanine-7)Platinum(II)
CAS No.	138180-67-3
Molecular Formula	C16H28N14O2Pt
Molecular Weight	683.59 g/mol
Synonyms	cis-Diamminebis(9-methyl-O6-methylguanine)platinum(II); Platinum, diamminebis[9-methyl-6-(methyloxy)-9H-purin-2-amine]-; cis-[Pt(NH3)2(9-Me-O6-Me-G)2]2+; cis-Diamminebis(9-methyl-O6-methylguanine)platinum(II); cis-Diammine-bis(O6,9-dimethylguanine)platinum(II); cis-DDP-O6,9-dimethylguanine derivative; Platinum complex with 9-methyl-O6-methylguanine
EINECS	Contact for details

Quality Control

Our cis-Diamminebis(O(6),9-Dimethylguanine-7)Platinum(II) is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	Yellow to orange solid powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Assay (Platinum content)	28.0% - 29.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.