Description

Methyl2-Deoxy-5-o-Pivaloyl-α-D-Threo-Pentofuranoside CAS NO 138147-42-9 is a high-purity, protected nucleoside derivative used as a critical building block in organic synthesis. This compound is essential for the development of novel pharmaceutical agents, particularly in antiviral and anticancer research. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in nucleoside chemistry and oligonucleotide synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of modified nucleosides and nucleotide analogs for drug discovery.
• Antiviral Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Anticancer Agent Development: Serves as a precursor for compounds designed to inhibit DNA replication in cancer cells.
• Oligonucleotide Synthesis: Acts as a protected monomer for the solid-phase synthesis of modified DNA/RNA strands.
• Biochemical Research: Employed in enzymatic studies and as a standard in analytical method development for nucleoside analysis.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for complex bioactive molecules.

Basic Information

Product Name	Methyl2-Deoxy-5-o-Pivaloyl-α-D-Threo-Pentofuranoside
CAS No.	138147-42-9
Molecular Formula	C12H22O5
Molecular Weight	246.30 g/mol
Synonyms	Methyl 2-Deoxy-5-O-pivaloyl-α-D-threo-pentofuranoside; 1-O-Methyl-2-deoxy-5-O-pivaloyl-α-D-threo-pentofuranose; 2-Deoxy-5-O-pivaloyl-α-D-threo-pentofuranoside Methyl Ester; α-D-Threo-Pentofuranoside, methyl 2-deoxy-5-O-pivaloyl-; Pivaloyl-protected deoxyribose derivative; Methyl 5-O-tert-butylcarbonyl-2-deoxy-α-D-threo-pentofuranoside
EINECS	Contact for details

Quality Control

Our Methyl2-Deoxy-5-o-Pivaloyl-α-D-Threo-Pentofuranoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.