Description

1-Pyridin-2-Ylmethylpiperidine-4-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and receptor-based therapies. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially in central nervous system (CNS) and GPCR-targeted research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for introducing the pyridinylmethylpiperidine moiety into more complex molecular architectures.
• Contract Manufacturing: Supplied to CDMOs for scale-up production under cGMP conditions for clinical trial material.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	1-Pyridin-2-Ylmethylpiperidine-4-Carboxylic Acid Ethyl Ester
CAS No.	138030-53-2
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	Ethyl 1-[(pyridin-2-yl)methyl]piperidine-4-carboxylate; 1-(Pyridin-2-ylmethyl)piperidine-4-carboxylic Acid Ethyl Ester; 4-Carbethoxy-1-(2-pyridylmethyl)piperidine; 1-(2-Pyridylmethyl)-4-piperidinecarboxylic Acid Ethyl Ester; 1-(Pyridin-2-Ylmethyl)piperidine-4-Carboxylic Acid Ethyl Ester; 1-(2-Pyridinylmethyl)-4-piperidinecarboxylic acid ethyl ester; Ethyl 1-(2-pyridinylmethyl)-4-piperidinecarboxylate; 138030-53-2
EINECS	Contact for details

Quality Control

Our 1-Pyridin-2-Ylmethylpiperidine-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.