Description

tert-Butyl Piperidine-4-Carboxylate is a versatile piperidine derivative and a crucial protected intermediate in advanced organic synthesis. Its primary value lies in providing a sterically hindered tert-butyl ester group, which offers excellent stability under a wide range of reaction conditions while remaining readily cleavable under acidic conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it serves as a key building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of various drug candidates, particularly those containing the piperidine pharmacophore.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the piperidine structure is a common motif.
• Organic Synthesis Reagent: Serves as a protected carboxylic acid precursor in multi-step synthetic routes, enabling selective reactions at other functional sites.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new chemical entities and reaction methodologies.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, flavors, and fragrances requiring high-purity intermediates.

Basic Information

Product Name	tert-Butyl Piperidine-4-Carboxylate
CAS No.	138007-24-6
Molecular Formula	C11H21NO2
Molecular Weight	199.29 g/mol
Synonyms	4-(tert-Butoxycarbonyl)piperidine; 1-Boc-4-piperidinecarboxylic acid; 1-Boc-piperidine-4-carboxylic acid; tert-Butyl 4-piperidinecarboxylate; 4-Carboxy-1-piperidinecarboxylic acid tert-butyl ester; 1-N-Boc-piperidine-4-carboxylic acid; Piperidine-4-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our tert-Butyl Piperidine-4-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, to verify identity and purity. A Certificate of Analysis (COA) detailing all relevant specifications is available with each shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.