Description

n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-o-[3,4,6-Tri-o-Acetyl-2-(Acetylamino)-2-Deoxy-α-D-Galactopyranosyl]-L-Serine Pentafluorophenyl Ester is a sophisticated, high-purity building block used in the synthesis of complex glycopeptides and glycoproteins. This compound is critical for researchers and manufacturers requiring precise glycosylation in peptide chains, enabling the study and development of novel therapeutics and diagnostic agents. It is primarily utilized in pharmaceutical R&D, particularly in the fields of oncology, immunology, and vaccine development, where controlled carbohydrate-protein conjugation is essential.

Application

• Glycopeptide Synthesis: A key activated ester intermediate for the solid-phase and solution-phase synthesis of O-linked glycopeptides.
• Pharmaceutical Research: Used in the development of targeted cancer therapies, immunotherapies, and synthetic vaccines that mimic natural glycoprotein structures.
• Bioconjugation: Enables the site-specific attachment of complex carbohydrate moieties to peptides, proteins, or other biomolecules for creating novel bioconjugates.
• Chemical Biology Probes: Serves as a precursor for synthesizing labeled glycopeptide probes to study carbohydrate-protein interactions and cell signaling pathways.
• Process Development: Employed in scaling up the production of glycosylated active pharmaceutical ingredients (APIs) under controlled GMP-like conditions.

Basic Information

Product Name	n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-o-[3,4,6-Tri-o-Acetyl-2-(Acetylamino)-2-Deoxy-α-D-Galactopyranosyl]-L-Serine Pentafluorophenyl Ester
CAS No.	137816-29-6
Molecular Formula	C38H37F5N2O13
Molecular Weight	824.70 g/mol
Synonyms	Fmoc-Ser(Ac3GalNAcα)-OPfp; Fmoc-L-Serine, O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-, 2,3,4,5,6-pentafluorophenyl ester, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; Fmoc-Ser[α-D-GalNAc(Ac)3]-OPfp Ester; Fmoc-O-(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl)-L-serine pentafluorophenyl ester; Glycosylated Fmoc-Amino Acid Pentafluorophenyl Ester; Ac3GalNAcα-Ser(Fmoc)-OPfp; 137816-29-6; Fmoc-Ser(Ac3-α-D-GalNAc)-OPfp
EINECS	Contact for details

Quality Control

Our n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-o-[3,4,6-Tri-o-Acetyl-2-(Acetylamino)-2-Deoxy-α-D-Galactopyranosyl]-L-Serine Pentafluorophenyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical testing including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.