Description

Carbamic Acid, Chloro(1,1-Dimethylethyl)-, Ethyl Ester (9Ci) is a specialized carbamate derivative primarily used as a key synthetic intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for introducing the tert-butyloxycarbonyl (Boc) protecting group with a chloro-substituted variant, enabling precise synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in peptide and heterocyclic chemistry.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the chloro and Boc functionalities are required.
• Peptide Chemistry: Serves as a specialized protecting group reagent for amino groups during solid-phase and solution-phase peptide synthesis (SPPS).
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for the introduction of the (chloro)tert-butoxycarbonyl group in complex molecule construction.
• Fine Chemical Production: Acts as a precursor in the manufacture of specialty chemicals, dyes, and functional materials.
• Bioconjugation Chemistry: Potential use in the development of linker molecules and probes for bioconjugation and labeling applications.

Basic Information

Product Name	Carbamic Acid, Chloro(1,1-Dimethylethyl)-, Ethyl Ester (9Ci)
CAS No.	137731-98-7
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	Ethyl N-(Chlorocarbonyl)-N-tert-butylcarbamate; tert-Butyl Chloroethyl Carbamate; N-(tert-Butoxycarbonyl)-N-chloroethylcarbamate; Boc-Chloroethylamine; Chloro-tert-butyl carbamate ethyl ester; 1,1-Dimethylethyl [chloro(ethoxy)methyl]carbamate; N-Chloro-N-(tert-butoxycarbonyl)ethylamine; (Chloro)(tert-butoxycarbonyl)amino Ethyl Ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, Chloro(1,1-Dimethylethyl)-, Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere if possible to maximize shelf-life stability, as the compound is light-sensitive.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.