Description

5H-Cyclopenta[C]Pyridine-4-Carboxylicacid,3-Amino-6,7-Dihydro-,Ethylester(9Ci) CAS NO 137676-51-8 is a high-purity, nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise chemical scaffold to construct complex molecular architectures for drug discovery programs targeting a range of therapeutic areas.

Application

This specialized pyridine derivative serves as a versatile intermediate in several high-value chemical synthesis pathways.

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Employed in the development of new generation pesticides and herbicides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and functionalized polymers.

Basic Information

Product Name	5H-Cyclopenta[C]Pyridine-4-Carboxylicacid,3-Amino-6,7-Dihydro-,Ethylester(9Ci)
CAS No.	137676-51-8
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	Ethyl 3-amino-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carboxylate; 3-Amino-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carboxylic acid ethyl ester; 5H-Cyclopenta[c]pyridine-4-carboxylic acid, 3-amino-6,7-dihydro-, ethyl ester; 137676-51-8; Ethyl 3-amino-4,5,6,7-tetrahydrocyclopenta[c]pyridine-4-carboxylate; 3-Amino-4,5,6,7-tetrahydrocyclopenta[c]pyridine-4-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and purity required for sensitive synthetic applications. All materials are characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.