Description

Methyl 3-Cyclobutyl-3-Oxopropanoate is a versatile β-keto ester building block characterized by its cyclobutyl ketone moiety. This compound is valued for its role as a key synthetic intermediate in the preparation of complex organic molecules, offering a reactive handle for further functionalization. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for applications in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing cyclobutane rings.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the cyclobutyl group imparts specific biological activity.
• Organic Synthesis Building Block: Employed in Claisen condensations, Michael additions, and other carbon-carbon bond-forming reactions to construct more complex molecular architectures.
• Fine Chemical Production: Acts as an intermediate in the manufacture of specialty chemicals, flavors, and fragrances.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and the exploration of new chemical spaces.

Basic Information

Product Name	Methyl 3-Cyclobutyl-3-Oxopropanoate
CAS No.	137638-05-2
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	Methyl 3-cyclobutyl-3-oxopropanoate; 3-Cyclobutyl-3-oxopropanoic acid methyl ester; Methyl cyclobutylpyruvate; Cyclobutyl pyruvic acid methyl ester; Methyl 3-cyclobutyl-3-oxopropionate; Acetic acid, 2-(cyclobutylcarbonyl)-, methyl ester; 2-(Cyclobutylcarbonyl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Cyclobutyl-3-Oxopropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.