Description

Ethyl 3-Chloro-4-Fluorobenzoate is a high-purity organic ester building block of significant importance in advanced chemical synthesis. This compound serves as a critical intermediate for the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific halogenated benzoate structure enables precise molecular modifications. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating libraries of bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the halogenated aromatic ring for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated and chlorinated aromatic components used in electronic displays.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, esterifications, and as a protecting group in multi-step synthetic routes in R&D laboratories.
• Polymer Modifier: Acts as a monomer or additive to introduce specific halogenated aromatic properties into polymer chains for specialty materials.

Basic Information

Product Name	Ethyl 3-Chloro-4-Fluorobenzoate
CAS No.	137521-81-4
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	Ethyl 3-Chloro-4-fluorobenzoate; Benzoic acid, 3-chloro-4-fluoro-, ethyl ester; 3-Chloro-4-fluorobenzoic acid ethyl ester; Ethyl 3-chloro-4-fluorobenzoate; 137521-81-4; Ethyl 3-chloro-4-fluorobenzenecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Chloro-4-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.