Description

Ethyl 4-Methanesulfonylcinnamate is a high-purity, synthetic organic compound belonging to the cinnamate ester family, featuring a methanesulfonyl (mesyl) substituent. This specific functionalization makes it a valuable key intermediate and building block in advanced chemical synthesis, particularly for pharmaceutical research and fine chemical manufacturing. It is primarily utilized by R&D chemists and process development scientists in the life sciences and specialty chemical sectors to develop novel active pharmaceutical ingredients (APIs) and functional materials.

Application

Ethyl 4-Methanesulfonylcinnamate serves as a versatile intermediate with applications across several high-value industries:

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting inflammatory pathways or acting as kinase inhibitors.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging its bioactivity and structural properties.
• Material Science: Acts as a monomer or functional additive in the research of specialty polymers and advanced organic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, to construct complex molecular architectures.
• Biochemical Research: Utilized as a substrate or probe in enzymatic studies and biochemical assay development.
• Fine Chemical Production: Serves as a starting material for synthesizing dyes, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Ethyl 4-Methanesulfonylcinnamate
CAS No.	137473-27-9
Molecular Formula	C₁₂H₁₄O₄S
Molecular Weight	254.30 g/mol
Synonyms	Ethyl (E)-3-[4-(methylsulfonyl)phenyl]acrylate; (E)-Ethyl 3-(4-(methylsulfonyl)phenyl)acrylate; 4-Methanesulfonylcinnamic Acid Ethyl Ester; Ethyl p-(Methylsulfonyl)cinnamate; Ethyl trans-4-(Methylsulfonyl)cinnamate; NSC 405124; AI3-52020
EINECS	Contact for details

Quality Control

Our Ethyl 4-Methanesulfonylcinnamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a synthesis intermediate. Standard testing includes identity confirmation by spectroscopic methods and purity determination by HPLC. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.